TIGP -- Design and Analytical Approaches for Conducting a Genome-Wide Association Study
- 講者張書瑋 教授 (長庚大學臨床資訊與醫學統計研究中心)
邀請人：TIGP Bioinformatics Program - 時間2013-03-28 (Thu.) 14:00 ~ 15:10
- 地點資訊所新館106演講廳
摘要
In this talk, I will focus on essential issues for designing and conducting a case-control genome-wide association study. An analytical work flow starting with data preparation, sample size and power consideration from both statistical and clinical perspectives will be discussed. The choice of genotyping chips, statistical testing and use of imputation will be evaluated. I will also review the strength, challenges and future opportunities of performing second-generation genome-wide association studies.